Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789781 | 0.91 | ESR1 (0.46) | GRM2ESR2ESR1MRGPRX4HPGD | |
| SCHEMBL7789815 | 0.90 | ESR1 (0.47) | GRM2ESR2ESR1MRGPRX4HPGD | |
| SCHEMBL1885756 | 0.86 | ESR2 (0.49) | GRM2ESR2ESR1HSD17B10MEN1 | |
| SCHEMBL7782054 | 0.86 | ESR2 (0.49) | GRM2ESR2ESR1HSD17B10MEN1 | |
| SCHEMBL7782033 | 0.85 | ESR2 (0.47) | GRM2ESR2ESR1MRGPRX4HSD17B10 | |
| SCHEMBL1888816 | 0.84 | MEN1 (0.51) | GRM2ESR2ESR1HSD17B10MEN1 | |
| SCHEMBL6572282 | 0.84 | MEN1 (0.51) | GRM2ESR2ESR1HSD17B10MEN1 | |
| Potassium SCHEMBL10738982 | 0.83 | MEN1 (0.50) | GRM2ESR2ESR1HSD17B10MEN1 | |
| SCHEMBL10738974 | 0.83 | MEN1 (0.50) | GRM2ESR2ESR1HSD17B10MEN1 | |
| Potassium Ion SCHEMBL10738962 | 0.82 | ESR2 (0.48) | GRM2ESR2ESR1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251898-B1 | Medical use of fluorenone derivatives for treating and preventing brain and spinal injury | QUESTCOR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |