Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966411 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPTHPGDMEN1 | |
| SCHEMBL7962499 | 0.82 | ALDH1A1 (0.35) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL7951953 | 0.82 | ALDH1A1 (0.34) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL9672501 | 0.81 | ALDH1A1 (0.44) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL8336632 | 0.81 | ALDH1A1 (0.38) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL7961321 | 0.79 | ALDH1A1 (0.36) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL7951853 | 0.77 | ALDH1A1 (0.50) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL7963270 | 0.77 | ALDH1A1 (0.51) | RARGALDH1A1TDP1MAPTHPGD | |
| SCHEMBL25231200 | 0.75 | EGFR (0.37) | RARGALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL30407021 | 0.75 | EGFR (0.37) | RARGALDH1A1L3MBTL1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761672-B1 | Cephalosporins containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | AVENTIS PHARMA SA (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| EP-0761672-A1 | Cephalosporin containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | ROUSSEL UCLAF (FR) | 1997-03-12 | — | — | EP | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |