⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897840 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL8960666 | 0.75 | — | — | |
| SCHEMBL12590732 | 0.75 | — | — | |
| SCHEMBL8648860 | 0.75 | — | — | |
| SCHEMBL9869603 | 0.72 | — | — | |
| SCHEMBL4595691 | 0.72 | TRPA1 (0.32) | — | |
| SCHEMBL1453853 | 0.71 | — | — | |
| SCHEMBL10365582 | 0.71 | — | — | |
| SCHEMBL1760715 | 0.69 | — | — | |
| SCHEMBL645473 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11033556-B2 | Bicyclic sulfonamides | ALIGOS THERAPEUTICS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200345749-A1 | BICYCLIC SULFONAMIDES | ALIGOS THERAPEUTICS, INC. | 2020-11-05 | — | — | US | disclosed |
| US-6251912-B1 | Substituted quinazoline derivatives | AMERICAN CYANAMID COMPANY | 2001-06-26 | — | — | US | disclosed |