Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.55 |
| ▸ | RARB | P10826 | 11/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.55 |
| ▸ | RARA | P10276 | 10/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.41 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.41 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.41 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784310 | 0.89 | RARG (0.51) | RARGRARBRXRARARA | |
| SCHEMBL2937025 | 0.88 | RARG (0.58) | RARGRARBRXRARARA | |
| SCHEMBL7794287 | 0.88 | RARB (0.60) | RARGRARBRXRARARA | |
| SCHEMBL7792837 | 0.88 | RARB (0.60) | RARGRARBRXRARARA | |
| SCHEMBL7784309 | 0.88 | RARB (0.60) | RARGRARBRXRARARA | |
| SCHEMBL7784321 | 0.87 | RARG (0.50) | RARGRARBRXRARARA | |
| SCHEMBL5847397 | 0.86 | RARG (0.69) | RARGRARBRXRARARA | |
| SCHEMBL7793751 | 0.84 | RARG (0.58) | RARGRARBRXRARARA | |
| SCHEMBL5845788 | 0.84 | RARG (0.60) | RARGRARBRXRARARACYP3A4 | |
| SCHEMBL7790156 | 0.84 | RARG (0.50) | RARGRARBRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |