Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.46 |
| ▸ | RARB | P10826 | 11/20 | 0.46 |
| ▸ | RARA | P10276 | 10/20 | 0.46 |
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789717 | 0.89 | EGFR (0.48) | RARGRARBRARARXRA | |
| SCHEMBL5847932 | 0.89 | RARB (0.56) | RARGRARBRARARXRA | |
| SCHEMBL7789719 | 0.88 | RARG (0.49) | RARGRARBRARARXRA | |
| SCHEMBL7784321 | 0.84 | RARG (0.50) | RARGRARBRARARXRA | |
| SCHEMBL7793745 | 0.84 | RARB (0.46) | RARGRARBRARARXRA | |
| SCHEMBL7794287 | 0.81 | RARB (0.60) | RARGRARBRARARXRARXRB | |
| SCHEMBL7792837 | 0.81 | RARB (0.60) | RARGRARBRARARXRARXRB | |
| SCHEMBL7784309 | 0.81 | RARB (0.60) | RARGRARBRARARXRARXRB | |
| SCHEMBL5846144 | 0.78 | EGFR (0.64) | RARGRARBRARARXRA | |
| SCHEMBL5847021 | 0.76 | RARB (0.59) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |