Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.46 |
| ▸ | RARG | P13631 | 13/20 | 0.46 |
| ▸ | RARA | P10276 | 12/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789719 | 0.88 | RARG (0.49) | RARBRARGRARARXRAMAPT | |
| SCHEMBL7792837 | 0.87 | RARB (0.60) | RARBRARGRARARXRA | |
| SCHEMBL7794287 | 0.87 | RARB (0.60) | RARBRARGRARARXRA | |
| SCHEMBL7784309 | 0.87 | RARB (0.60) | RARBRARGRARARXRA | |
| SCHEMBL5846462 | 0.86 | RARB (0.61) | RARBRARGRARARXRAEGFR | |
| SCHEMBL7793750 | 0.86 | RARB (0.47) | RARBRARGRARARXRAEGFR | |
| SCHEMBL7789717 | 0.84 | EGFR (0.48) | RARBRARGRARARXRAEGFR | |
| SCHEMBL7790168 | 0.84 | RARG (0.46) | RARBRARGRARARXRA | |
| SCHEMBL2945902 | 0.83 | RARB (0.54) | RARBRARGRARARXRALMNA | |
| SCHEMBL2943885 | 0.83 | RARG (0.58) | RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |