Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790190 | 0.93 | KLK7 (0.40) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL7790063 | 0.91 | FKBP1A (0.41) | FKBP1AKLK7CTSLF2CASP1 | |
| SCHEMBL31486301 | 0.88 | FKBP1A (0.44) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL22446555 | 0.86 | KLK7 (0.45) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL30387086 | 0.86 | KLK7 (0.45) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL31486524 | 0.86 | KLK7 (0.45) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL12643706 | 0.86 | KLK7 (0.45) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL23121510 | 0.84 | FKBP1A (0.42) | FKBP1AKLK7CTSLF2KLK5 | |
| SCHEMBL31486416 | 0.81 | FKBP1A (0.45) | FKBP1AKLK7CTSLF2HPGD | |
| SCHEMBL31107722 | 0.81 | FKBP1A (0.45) | FKBP1AKLK7CTSLF2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826663-B1 | Alkynylamino acid derivatives and their use as pharmaceutical compounds | LILLY CO ELI (GB) | 2001-10-31 | — | — | EP | disclosed |
| EP-0826663-A2 | Alkynylamino acid derivatives and their use as pharmaceutical compounds | ELI LILLY AND COMPANY LIMITED (GB) | 1998-03-04 | — | — | EP | disclosed |