Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.73 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 2/20 | 0.32 |
| ▸ | PDIA4 | P13667 | 2/20 | 0.32 |
| ▸ | PDIA3 | P30101 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789896 | 1.00 | TOP2A (0.73) | TOP2ATOP2BCYP3A4CYP2D6RPS6KA3 | |
| SCHEMBL7784492 | 1.00 | TOP2A (0.73) | TOP2ATOP2BCYP3A4CYP2D6RPS6KA3 | |
| SCHEMBL7789970 | 1.00 | TOP2A (0.73) | TOP2ATOP2BCYP3A4CYP2D6RPS6KA3 | |
| SCHEMBL7789965 | 0.90 | TOP2A (0.69) | TOP2ATOP2B | |
| SCHEMBL7784472 | 0.90 | TOP2A (0.63) | TOP2ATOP2BCYP3A4CYP2D6RPS6KA3 | |
| SCHEMBL7790550 | 0.89 | TOP2A (0.71) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7790425 | 0.89 | TOP2A (0.71) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7794023 | 0.88 | TOP2A (0.64) | TOP2ATOP2BP4HBPDIA4PDIA3 | |
| SCHEMBL7794516 | 0.88 | TOP2A (0.64) | TOP2ATOP2BP4HBPDIA4PDIA3 | |
| SCHEMBL7789932 | 0.88 | TOP2A (0.64) | TOP2ATOP2BP4HBPDIA4PDIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156056-A1 | 5-GLYCOSYLOXY-6-HYDROXYNAPHTHO 2,3-f]QUINOLINE-7,12-DIONE HAVING ANTICANCER ACTIVITIES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-11-21 | — | — | EP | disclosed |