Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.71 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790450 | 1.00 | TOP2A (0.71) | TOP2ATOP2BTDP1KDM4ENSD2 | |
| SCHEMBL7790425 | 1.00 | TOP2A (0.71) | TOP2ATOP2BTDP1KDM4ENSD2 | |
| SCHEMBL7793233 | 0.94 | TOP2A (0.75) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7784478 | 0.94 | TOP2A (0.76) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7793983 | 0.94 | TOP2A (0.76) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7784483 | 0.91 | TOP2A (0.58) | TOP2ATOP2BTDP1 | |
| SCHEMBL7790428 | 0.89 | TOP2A (0.73) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7789896 | 0.89 | TOP2A (0.73) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7784492 | 0.89 | TOP2A (0.73) | TOP2ATOP2BTDP1KDM4EMAPT | |
| SCHEMBL7789970 | 0.89 | TOP2A (0.73) | TOP2ATOP2BTDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156056-A1 | 5-GLYCOSYLOXY-6-HYDROXYNAPHTHO 2,3-f]QUINOLINE-7,12-DIONE HAVING ANTICANCER ACTIVITIES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-11-21 | — | — | EP | claimed |
| EP-1156056-A1 | 5-GLYCOSYLOXY-6-HYDROXYNAPHTHO 2,3-f]QUINOLINE-7,12-DIONE HAVING ANTICANCER ACTIVITIES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-11-21 | — | — | EP | disclosed |