Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397548 | 0.82 | TDP1 (0.56) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10688991 | 0.78 | TDP1 (0.52) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10688994 | 0.78 | TDP1 (0.52) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8866182 | 0.77 | TDP1 (0.50) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5623488 | 0.77 | TDP1 (0.50) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2097650 | 0.75 | TDP1 (0.65) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL436853 | 0.75 | TDP1 (0.48) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8580636 | 0.73 | TDP1 (0.62) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10948851 | 0.72 | TDP1 (0.46) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7503380 | 0.71 | TDP1 (0.60) | TDP1TP53GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965256-A | ENHANCED DURATION OF ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | claimed |
| CN-109574797-A | A kind of preparation method of chirality benzylalcohol | 上海彩迩文生化科技有限公司 | 2019-04-05 | — | — | CN | disclosed |
| EP-0763513-B1 | Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide | NIHON NOHYAKU CO LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1026135-A1 | Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide | Nihon Nohyaku Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5981807-A | REACTING A HALO-SUBSTITUTED PHENYLETHANOL WITH PHTHALIC ANHYDRIDE, PERFORMING OPTICAL RESOLUTION ON THE RESULTING COMPOUND USING AN OPTICALLY ACTIVE ORGANIC AMINE AS A RESOLVING AGENT, PERFORMING HYDROLYSIS OR ALCOHOLYSIS | NIHON NOHYAKU CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5756862-A | RACEMIZATION WITH ACID CATALYST | NIHON NOHYAKU CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0763513-A2 | Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide | Nihon Nohyaku Co., Ltd. (JP) | 1997-03-19 | — | — | EP | disclosed |