SCHEMBL77906

SCHEMBL77906

O=c1n(Cc2cc(C3CCCCC3)c(O)c(C3CCCCC3)c2)c(=O)n(Cc2cc(C3CCCCC3)c(O)c(C3CCCCC3)c2)c(=O)n1Cc1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.42
BACE1 P56817 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
HSP90AA1 P07900 1/20 0.36
CCNE1 P24864 3/20 0.35
CDK2 P24941 3/20 0.35
GRM2 Q14416 1/20 0.34
NR1I2 O75469 1/20 0.34
KDM4B O94953 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
ADRA1A P35348 1/20 0.34
DOHH Q9BU89 1/20 0.34
GAA P10253 1/20 0.34
PDE5A O76074 4/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10566115 0.91 PDE5A (0.38) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL10563172 0.91 PDE5A (0.38) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL10565334 0.90 PDE5A (0.39) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL10566223 0.88 PDE5A (0.38) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL10564840 0.88 PDE5A (0.38) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9763392 0.88 ALDH1A1 (0.51) KDM4EMEN1MAPTKMT2AGAA
SCHEMBL9763791 0.88 ALDH1A1 (0.51) KDM4EMEN1MAPTKMT2AGAA
SCHEMBL9764226 0.86 ALDH1A1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL5095362 0.85 KMT2A (0.37) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL10567861 0.85 ALDH1A1 (0.51) KDM4EMEN1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2467 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182674-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-06-06 US claimed
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US claimed
EP-4308638-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING POLYOLEFIN RECYCLATES, STABILIZER COMPOSITION, MASTER BATCH CONCENTRATE, PLASTIC COMPOSITION, MOLDING COMPOUND OR MOLDING, METHOD FOR STABILIZING A POLYOLEFIN RECYCLATE AND USE OF A PLASTIC COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-24 EP claimed
EP-4301809-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-10 EP claimed
WO-2022194672-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING POLYOLEFIN RECYCLATES, STABILIZER COMPOSITION, MASTER BATCH CONCENTRATE, PLASTIC COMPOSITION, MOLDING COMPOUND OR MOLDING, METHOD FOR STABILIZING A POLYOLEFIN RECYCLATE AND USE OF A PLASTIC COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-22 WO claimed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP claimed
US-9181481-B2 Liquid crystal display device and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-10 US claimed
US-8258214-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-09-04 US claimed
EP-2491078-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING Chemtura Corporation (US) 2012-08-29 EP claimed
US-8188170-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-05-29 US claimed
US-20120035305-A1 Polymers with Low Gel Content and Enhanced Gas-Fading SI GROUP, INC. 2012-02-09 US claimed
WO-2011049728-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2011-04-28 WO claimed
US-20100197837-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2010-08-05 US claimed
EP-1925628-A1 Process for polyolefin silane crosslinking Ciba Holding Inc. (CH) 2008-05-28 EP claimed
EP-0905180-B1 Dust free stabiliser granules containing epoxide and process of their preparation CIBA SC HOLDING AG (CH) 2003-05-21 EP claimed
US-20010044518-A1 Plastic additives, comprising a phenolic antioxidant, organic phosphite or phosphonite, a phosphonate, a sterically hindered amine or a UV absorber, or mixture thereof, and an epoxy compound solid at room temperature HOFFMANN KURT (DE) 2001-11-22 US claimed
EP-0921940-A1 LAMINATED GLASS RESISTANT TO UV RADIATION Glace Controle (FR) 1999-06-16 EP claimed
WO-1998055294-A1 LAMINATED GLASS RESISTANT TO UV RADIATION GLACE CONTROLE (FR) 1998-12-10 WO claimed
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF ENALARE THERAPEUTICS INC (US) 2024-07-18 US disclosed
EP-0250363-A2 Triazine derivatives of piperidinylamidines CIBA-GEIGY AG (CH) 1987-12-23 EP disclosed