Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589419 | 0.87 | CYP3A4 (0.40) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL27254682 | 0.86 | ALDH1A1 (0.37) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17622936 | 0.82 | CYP3A4 (0.34) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17526995 | 0.81 | ALDH1A1 (0.50) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17526799 | 0.81 | ALDH1A1 (0.50) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL11989346 | 0.81 | ALDH1A1 (0.50) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17323472 | 0.80 | CYP3A4 (0.33) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17323467 | 0.80 | CYP3A4 (0.33) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL12321695 | 0.80 | ALDH1A1 (0.39) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17526649 | 0.79 | CYP3A4 (0.44) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |