SCHEMBL7790705

SCHEMBL7790705

NCCOB(O)c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.49
CA12 O43570 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
TRPM2 O94759 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953133 0.85 HTR1B (0.40) HTR1BALDH1A1TSHRKDM4EHPGD
SCHEMBL5952005 0.82 KDM4E (0.44) HTR1BALDH1A1TSHRKDM4EHPGD
SCHEMBL5952349 0.79 HPGD (0.44) ALDH1A1TSHRKDM4EHPGDCYP1A2
SCHEMBL22635045 0.76 CYP1A2 (0.43) ALDH1A1TSHRKDM4EHPGDCYP1A2
SCHEMBL13383570 0.76 ALDH1A1 (0.49) HTR1BCA12CA3CA4CA6
SCHEMBL7784917 0.76 TSHR (0.43) ALDH1A1TSHRKDM4EHPGDCYP1A2
SCHEMBL7655382 0.75 ALDH1A1 (0.36) CA12CA4CA7CA9CA14
SCHEMBL2398660 0.75 HTR1B (0.51) HTR1BCA12CA3CA4CA6
SCHEMBL28932400 0.75 TAAR1 (0.44) ALDH1A1TSHRKDM4EHPGDCYP1A2
SCHEMBL28500816 0.73 MAPK1 (0.47) ALDH1A1TSHRKDM4EHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed