Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794484 | 0.73 | HTR2A (0.32) | HTR2A | |
| SCHEMBL217948 | 0.71 | BRD4 (0.32) | HTR2A | |
| SCHEMBL7794633 | 0.71 | HTR2A (0.31) | HTR2A | |
| SCHEMBL7794530 | 0.71 | DYRK1A (0.39) | — | |
| SCHEMBL27543320 | 0.70 | KDM1A (0.32) | — | |
| SCHEMBL7785076 | 0.70 | POLB (0.36) | MEN1KMT2A | |
| SCHEMBL23092050 | 0.69 | ATM (0.39) | HTR2AGAA | |
| SCHEMBL1030002 | 0.68 | — | — | |
| SCHEMBL1026826 | 0.67 | PRCP (0.32) | — | |
| SCHEMBL7794577 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1896078-A | Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2007-01-17 | — | — | CN | disclosed |
| CN-1264846-C | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1473163-A | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | — | 2004-02-04 | — | — | CN | disclosed |
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |