SCHEMBL7794530

SCHEMBL7794530

Oc1ccc2c(c1)C=[C]C2O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.39
HSD17B10 Q99714 2/20 0.33
CA2 P00918 2/20 0.33
CA5A P35218 2/20 0.33
CA12 O43570 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
SHBG P04278 1/20 0.31
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790709 0.71 MAOA (0.33)
SCHEMBL8009827 0.67 CHRNB2 (0.33) DYRK1AHSD17B10CA2CA5ACA12
SCHEMBL29034034 0.64 SHBG (0.43) DYRK1AHSD17B10CA2CA5ACA12
SCHEMBL18722280 0.61 DYRK1A (0.46) DYRK1AHSD17B10CA2CA5ACA12
SCHEMBL13403837 0.61 HSD17B10 (0.41) HSD17B10CA2CA5ACA12ALDH1A1
SCHEMBL7459638 0.59 CHRNB2 (0.50) DYRK1AHSD17B10CA2CA5ACA12
SCHEMBL21032529 0.57 MAOA (0.52) DYRK1AHSD17B10CA2CA5AALDH1A1
SCHEMBL8405009 0.56
Inositol SCHEMBL8071615 0.56 CA12 (0.75) HSD17B10CA2CA5ACA12ALDH1A1
SCHEMBL11148197 0.55 CHRNB2 (0.45) DYRK1AHSD17B10CA2CA5ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed