Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.72 |
| ▸ | CCR5 | P51681 | 3/20 | 0.72 |
| ▸ | CCR8 | P51685 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terpyridine SCHEMBL7795085 | 0.85 | KDM4E (0.67) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL517337 | 0.85 | CCR1 (1.00) | CCR1CCR5CCR8KDM4ELMNA | |
| 2-Mercaptoethanol SCHEMBL7790768 | 0.84 | CCR1 (0.72) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL1617719 | 0.83 | CCR1 (0.96) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7552182 | 0.80 | CCR1 (0.82) | CCR1CCR5CCR8KDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL7544617 | 0.79 | CCR1 (0.79) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7790733 | 0.78 | CCR1 (0.77) | CCR1CCR5CCR8KDM4ELMNA | |
| Terpyridine SCHEMBL30883364 | 0.77 | KDM4E (0.55) | CCR1CCR5CCR8KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL28907429 | 0.75 | CCR1 (0.79) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL4889156 | 0.74 | CCR1 (0.77) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155025-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050431-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |