SCHEMBL517337

SCHEMBL517337

Clc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 1.00
CCR5 P51681 3/20 1.00
CCR8 P51685 3/20 1.00
KDM4E B2RXH2 7/20 0.64
TP53 P04637 5/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
LMNA P02545 3/20 0.64
ALOX15 P16050 2/20 0.64
HTT P42858 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
ALPL P05186 1/20 0.64
HSP90AA1 P07900 1/20 0.64
ALPI P09923 1/20 0.64
ALPG P10696 1/20 0.64
MAPK1 P28482 1/20 0.64
METAP1 P53582 2/20 0.61
CYP1A2 P05177 2/20 0.61
POLB P06746 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1617719 0.98 CCR1 (0.96) CCR1CCR5CCR8KDM4ETP53
SCHEMBL7552182 0.91 CCR1 (0.82) CCR1CCR5CCR8KDM4ETP53
Ammonia Solution, Strong SCHEMBL7544617 0.89 CCR1 (0.79) CCR1CCR5CCR8KDM4ETP53
Hydrochloric Acid SCHEMBL28907429 0.88 CCR1 (0.79) CCR1CCR5CCR8KDM4ETP53
SCHEMBL7790733 0.88 CCR1 (0.77) CCR1CCR5CCR8KDM4ETP53
SCHEMBL4889156 0.88 CCR1 (0.77) CCR1CCR5CCR8KDM4ETP53
SCHEMBL7109447 0.86 CCR1 (0.74) CCR1CCR5CCR8KDM4ETP53
2-Mercaptoethanol SCHEMBL7790768 0.85 CCR1 (0.72) CCR1CCR5CCR8KDM4ETP53
2-Mercaptoethanol SCHEMBL7790771 0.85 CCR1 (0.72) CCR1CCR5CCR8KDM4ETP53
SCHEMBL1993385 0.84 CCR1 (0.72) CCR1CCR5CCR8KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895280-A Photosensitive silk fibroin hydrogel and preparation method and application thereof 南通大学 2023-04-04 CN claimed
EP-0885233-B1 TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION (GB) 2002-06-19 EP claimed
US-12545679-B2 Compound, material for an organic electroluminescence device and an organic electroluminescence device comprising the compound IDEMITSU KOSAN CO., LTD. (JP) 2026-02-10 US disclosed
EP-4656637-A1 COMPOUND, AND LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE AND PHOTOSENSITIZER EACH CONTAINING SAME Toray Industries, Inc. (JP) 2025-12-03 EP disclosed
US-12486344-B2 Non-thiol nitrogen based hydrophobic polymer brush materials and use thereof for modification of substrate surfaces MERCK PATENT GMBH (DE) 2025-12-02 US disclosed
EP-4634168-A1 TRANSITION METAL COMPLEXES AS VISIBLE LIGHT ABSORBERS Johnson & Johnson Vision Care, Inc. (US) 2025-10-22 EP disclosed
US-12398243-B2 Block polymer composite membranes UNIVERSITY OF NOTRE DAME DU LAC (US) 2025-08-26 US disclosed
US-12258353-B2 Heterocyclic compound and organic light-emitting element including same LT MATERIALS CO., LTD. (KR) 2025-03-25 US disclosed
US-12252485-B2 Heterocyclic compound and organic light emitting device comprising same LT MATERIALS CO., LTD. (KR) 2025-03-18 US disclosed
WO-2025043301-A1 METAL-BINDING COMPOUNDS AND METAL COMPLEXES, METHODS OF THEIR PREPARATION, AND USES IN THE COMPLEXING OF METAL IONS QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2025-03-06 WO disclosed
EP-3799143-B1 FIRST AND SECOND ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2024-09-11 EP disclosed
WO-2000050431-A1 PLATINUM (II) COMPOUNDS ISIS INNOVATION LIMITED (GB) 2000-08-31 WO disclosed
WO-2000043405-A1 BIS-TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION LIMITED (GB) 2000-07-27 WO disclosed
US-6013802-A AS FLUROESCENT INDICATORS FOR DETECTION AND QUANTIFICATION OF METAL IONS MOLECULAR PROBES, INC. (US) 2000-01-11 US disclosed
US-5863919-A Lock and key micelles and monomer building blocks therefor UNIVERSITY OF SOUTH FLORIDA (US) 1999-01-26 US disclosed
EP-0885233-A1 TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION LIMITED (GB) 1998-12-23 EP disclosed
WO-1997027202-A1 TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION LIMITED (GB) 1997-07-31 WO disclosed
US-5650101-A Lock and key micelles UNIVERSITY OF SOUTH FLORIDA (US) 1997-07-22 US disclosed
US-5648270-A FLUORESCENT INDICATORS USING METAL-PYRIDINE COMPLEXES MOLECULAR PROBES, INC. (US) 1997-07-15 US disclosed
WO-1996003114-A1 LOCK AND KEY MICELLES UNIVERSITY OF SOUTH FLORIDA (US) 1996-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252485-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CYP1A1, CYP1B1 CCR1 1738/4885CCR5 2950/4885CCR8 3481/4885
US-12545679-B2 Compound, material for an organic electroluminescence device and an organic electroluminescence device comprising the compound KCNJ2, KCNH1, KCNH2 CCR1 1288/4885CCR5 1729/4885CCR8 2211/4885
US-12258353-B2 Heterocyclic compound and organic light-emitting element including same CRY1, CRY2, LEF1 CCR1 2489/4885CCR5 3844/4885CCR8 3157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.