SCHEMBL7790776

SCHEMBL7790776

Cc1cc([N+](=O)[O-])c(OC(C)CO)c([N+](=O)[O-])c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
PDGFRB P09619 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33
FLT1 P17948 1/20 0.33
FGFR3 P22607 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793069 0.82 ALDH1A1 (0.36) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7792790 0.81 TDP1 (0.40) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7789238 0.80 TSHR (0.39) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7787975 0.79 CYP1A2 (0.41) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7789242 0.78 ALDH1A1 (0.38) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7789248 0.77 CYP1A2 (0.41) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7783056 0.76 CYP1A2 (0.41) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL8645578 0.76 TSHR (0.59) CYP1A2TDP1ALDH1A1TSHRGRIN2D
SCHEMBL7789681 0.75 ALDH1A1 (0.34) CYP1A2TDP1ALDH1A1TSHRHTT
SCHEMBL8651063 0.75 CYP1A2 (0.45) CYP1A2TDP1ALDH1A1TSHRGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889026-B1 Alpha-phenoxy alkanols, processes for their preparation and their uses CFPI NUFARM (FR) 2001-11-14 EP disclosed
US-6090984-A PREPARATION FROM 2,6-DINITRO-3,4-DIMETHYLPHENOL ETHYLENE OXIDE, PROPYLENE OXIDE OR 2,3-EPOXYBUTANE; REACTING AN ALPHA-PHENOXYALKANOL WITH 3-AMINOPENTANE TO FORM PENDIMETHALIN. CFPI AGRO (FR) 2000-07-18 US disclosed
EP-0889026-A1 Alpha-phenoxy alkanols, processes for their preparation and their uses CFPI AGRO (FR) 1999-01-07 EP disclosed