Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 13/20 | 0.91 |
| ▸ | PPIA | P62937 | 5/20 | 0.90 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.90 |
| ▸ | PPP3CA | Q08209 | 2/20 | 0.90 |
| ▸ | MEN1 | O00255 | 1/20 | 0.90 |
| ▸ | NPC1 | O15118 | 1/20 | 0.90 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.90 |
| ▸ | GMNN | O75496 | 1/20 | 0.90 |
| ▸ | USP2 | O75604 | 1/20 | 0.90 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.90 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.90 |
| ▸ | MAPT | P10636 | 1/20 | 0.90 |
| ▸ | RARB | P10826 | 1/20 | 0.90 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.90 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.90 |
| ▸ | TACR2 | P21452 | 1/20 | 0.90 |
| ▸ | PPIB | P23284 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geclosporin SCHEMBL2110698 | 1.00 | ABCB1 (0.91) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL18737282 | 0.96 | ABCB1 (0.85) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL23110295 | 0.96 | PPIA (0.89) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL16274167 | 0.95 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL17921935 | 0.95 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL13652544 | 0.95 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL22840735 | 0.95 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL23110210 | 0.95 | ABCB1 (1.00) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| Cyclosporine SCHEMBL24239446 | 0.95 | ABCB1 (1.00) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| Cyclosporine SCHEMBL24224445 | 0.95 | ABCB1 (1.00) | ABCB1PPIAFKBP1BPPP3CAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3641798-B1 | COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | AKI THERAPEUTICS APS (DK) | 2026-01-21 | — | — | EP | claimed |
| EP-3556774-B1 | ANTI-CD40 ANTIBODIES AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2024-01-03 | — | — | EP | claimed |
| CN-116063481-A | Humanized anti-CD 40 antibodies and uses thereof | 普里玛托普医疗股份有限公司 | 2023-05-05 | — | — | CN | claimed |
| US-11471445-B2 | Compositions for the prevention and treatment of acute renal injury | AKI THERAPEUTICS APS (DK) | 2022-10-18 | — | — | US | claimed |
| CN-109069621-B | Humanized anti-CD 40 antibodies and uses thereof | 普里玛托普医疗股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-114514019-A | Method for producing pharmaceutical preparations containing crystalline and amorphous fractions of active substances | 拜耳股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| US-20210330649-A1 | COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | AKI THERAPEUTICS APS (DK) | 2021-10-28 | — | — | US | claimed |
| CN-112120033-A | Application of ophiosporin G in preparation of marine fouling organism control agent | 中国科学院南海海洋研究所 | 2020-12-25 | — | — | CN | claimed |
| EP-3641798-A1 | COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | AKI THERAPEUTICS APS (DK) | 2020-04-29 | — | — | EP | claimed |
| CN-110996985-A | Composition for preventing and treating acute kidney injury | AKI医疗有限公司 | 2020-04-10 | — | — | CN | claimed |
| EP-0512109-A1 | ORAL PHARMACEUTICAL COMPOSITION CONTAINING CYCLOSPORIN AND PROCESS FOR PREPARING SAME. | BIOGAL GYOGYSZERGYAR (HU) | 1992-11-11 | — | — | EP | claimed |
| WO-1992018105-A1 | IMPROVEMENTS IN PHARMACEUTICAL COMPOSITIONS | SANDOZ LTD. (CH) | 1992-10-29 | — | — | WO | claimed |
| EP-0506840-A1 | METHOD OF TREATING OCULAR DISEASES BY PERIOCULAR ADMINISTRATION OF CYCLOSPORINE A OR G | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1992-10-07 | — | — | EP | claimed |
| WO-1992016226-A1 | IL-1 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-10-01 | — | — | WO | claimed |
| WO-1992009299-A1 | ORAL PHARMACEUTICAL COMPOSITION CONTAINING CYCLOSPORIN AND PROCESS FOR PREPARING SAME | BIOGAL Gyógyszergyár Rt. (HU) | 1992-06-11 | — | — | WO | claimed |
| US-5051402-A | Fungicides, immunosuppressants and antiphlogistic agents | SANKYO COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | claimed |
| US-5047396-A | Cyclosporins, monester of hydroxylated fatty acid with ethylene glycol and mono or polyvalent alcohols | BIOGAL GYOGYSZERGYAR (HU) | 1991-09-10 | — | — | US | claimed |
| WO-1991008757-A1 | METHOD OF TREATING OCULAR DISEASES BY PERIOCULAR ADMINISTRATION OF CYCLOSPORINE A OR G | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1991-06-27 | — | — | WO | claimed |
| WO-1990000389-A1 | FREEZE-DRIED LIPOSOME COMPOSITIONS CONTAINING CYCLOSPORIN | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-01-25 | — | — | WO | claimed |
| US-4288431-A | CULTURING TOLYPLOCLADIUM, CATALYTIC HYDROGENATION, REARRANGEMENT; ANTIINFLAMMATORY, IMMUNOLOGY | SANDOZ LTD. (CH) | 1981-09-08 | — | — | US | claimed |