Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 13/20 | 0.85 |
| ▸ | PPIA | P62937 | 5/20 | 0.83 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.83 |
| ▸ | PPP3CA | Q08209 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 1/20 | 0.83 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.83 |
| ▸ | GMNN | O75496 | 1/20 | 0.83 |
| ▸ | USP2 | O75604 | 1/20 | 0.83 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.83 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | POLB | P06746 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | RARB | P10826 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.83 |
| ▸ | TACR2 | P21452 | 1/20 | 0.83 |
| ▸ | PPIB | P23284 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geclosporin SCHEMBL2110698 | 0.96 | ABCB1 (0.91) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| Geclosporin SCHEMBL7791 | 0.96 | ABCB1 (0.91) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL18720089 | 0.96 | ABCB1 (0.91) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL17921935 | 0.93 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL22840735 | 0.93 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL18737000 | 0.93 | ABCB1 (0.86) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL23110295 | 0.92 | PPIA (0.89) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL16274167 | 0.92 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| SCHEMBL13652544 | 0.92 | ABCB1 (0.94) | ABCB1PPIAFKBP1BPPP3CAMEN1 | |
| Cyclosporine SCHEMBL4459071 | 0.91 | ABCB1 (0.97) | ABCB1PPIAFKBP1BPPP3CAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101445-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL INC. | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101445-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | HAVCR2, TSLP, HLA-DRB1 | ABCB1 198/4885PPIA 610/4885FKBP1B 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.