Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986982 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| SCHEMBL5988345 | 0.76 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| SCHEMBL5288 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4967118 | 0.74 | — | — | |
| SCHEMBL226224 | 0.73 | — | — | |
| SCHEMBL9311644 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| Methylene Chloride SCHEMBL28182290 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| SCHEMBL11049219 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| SCHEMBL27559806 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10SMN1; SMN2CHRM5 | |
| SCHEMBL6640135 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |