Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.47 |
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787617 | 0.84 | ESR2 (0.44) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL10529811 | 0.83 | ESR2 (0.54) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL7787631 | 0.79 | ESR2 (0.52) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL7787618 | 0.79 | ESR2 (0.52) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL7983269 | 0.78 | ESR2 (0.49) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL1885756 | 0.78 | ESR2 (0.49) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL7782054 | 0.78 | ESR2 (0.49) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL10738969 | 0.78 | ESR2 (0.51) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL10793657 | 0.78 | ESR2 (0.51) | ESR2ESR1MEN1ALOX15TSHR | |
| SCHEMBL10793663 | 0.78 | ESR2 (0.51) | ESR2ESR1MEN1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251898-B1 | Medical use of fluorenone derivatives for treating and preventing brain and spinal injury | QUESTCOR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |