SCHEMBL7791350

SCHEMBL7791350

O=C[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 9/20 0.64
NR1H4 Q96RI1 7/20 0.57
PPARG P37231 3/20 0.57
PPARD Q03181 1/20 0.57
PPARA Q07869 1/20 0.57
SLC16A3 O15427 1/20 0.49
DHODH Q02127 1/20 0.49
CCKAR P32238 1/20 0.48
CCKBR P32239 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789992 0.84 NR1H4 (0.58) CAPN1NR1H4
SCHEMBL7789989 0.84 NR1H4 (0.58) CAPN1NR1H4
SCHEMBL24133346 0.84 CCKAR (0.67) NR1H4PPARGPPARDPPARACCKAR
SCHEMBL30272388 0.84 CCKAR (0.67) NR1H4PPARGPPARDPPARACCKAR
SCHEMBL24133353 0.81 NR1H4 (0.55) NR1H4PPARGPPARDPPARACCKAR
SCHEMBL30272375 0.81 NR1H4 (0.55) NR1H4PPARGPPARDPPARACCKAR
SCHEMBL6793785 0.80 DEGS1 (0.56) CAPN1
SCHEMBL6793788 0.80 DEGS1 (0.56) CAPN1
SCHEMBL7384115 0.80 CAPN1 (0.60) CAPN1SLC16A3
SCHEMBL7791340 0.80 CAPN1 (0.60) CAPN1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251917-B1 Benzamidoaldehydes and their use as cysteine protease inhibitors BASF AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed