Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.57 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789992 | 1.00 | NR1H4 (0.58) | NR1H4CAPN1DEGS1MEN1KMT2A | |
| SCHEMBL7789993 | 0.85 | NR1H4 (0.62) | NR1H4CAPN1PIN1 | |
| SCHEMBL7791350 | 0.84 | CAPN1 (0.64) | NR1H4CAPN1 | |
| SCHEMBL6793785 | 0.84 | DEGS1 (0.56) | CAPN1DEGS1MEN1KMT2ANPC1 | |
| SCHEMBL6793788 | 0.84 | DEGS1 (0.56) | CAPN1DEGS1MEN1KMT2ANPC1 | |
| SCHEMBL7789871 | 0.83 | PIN1 (0.60) | NR1H4DEGS1MEN1KMT2ANPC1 | |
| SCHEMBL7789870 | 0.83 | PIN1 (0.60) | NR1H4DEGS1MEN1KMT2ANPC1 | |
| SCHEMBL7790056 | 0.83 | CAPN1 (0.74) | CAPN1PIN1 | |
| SCHEMBL7787807 | 0.82 | ALDH1A1 (0.56) | CAPN1MEN1KMT2AGPR27PLAU | |
| SCHEMBL7787808 | 0.82 | ALDH1A1 (0.56) | CAPN1MEN1KMT2AGPR27PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |