SCHEMBL7791391

SCHEMBL7791391

c1ccc(Oc2ccccc2Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.69
NCOA3 Q9Y6Q9 1/20 0.69
PTGS2 P35354 1/20 0.59
BRD4 O60885 3/20 0.51
FFAR4 Q5NUL3 2/20 0.51
HTR1A P08908 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
LTA4H P09960 1/20 0.46
TSHR P16473 1/20 0.46
AR P10275 1/20 0.45
MAPK1 P28482 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
GSTP1 P09211 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10755935 1.00 NCOA1 (0.69) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL1958156 0.96 NCOA1 (0.74) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL10756496 0.91 NCOA1 (0.61) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL11833811 0.89 NCOA1 (0.53) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL112422 0.89 NCOA1 (0.63) NCOA1NCOA3PTGS2FFAR4AR
Bicarbonate SCHEMBL28250947 0.88 NCOA1 (0.65) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL10711068 0.87 NCOA1 (0.69) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL3430781 0.87 NCOA1 (0.63) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL9208935 0.87 NCOA1 (0.75) NCOA1NCOA3PTGS2BRD4FFAR4
SCHEMBL28431579 0.86 NCOA1 (0.61) NCOA1NCOA3PTGS2BRD4FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63095244-A None JP disclosed
JP-62109840-A None JP disclosed
JP-59100197-A None JP disclosed
JP-63095245-A None JP disclosed
JP-9125085-A None JP disclosed
JP-2001081486-A LUBRICATING OIL ISHIKAWAJIMA HARIMA HEAVY IND CO LTD 2001-03-27 JP disclosed
JP-H09125085-A HEAT-RESISTANT LUBRICATING OIL COMPOSITION TONEN CORP 1997-05-13 JP disclosed
JP-S6395244-A POLYPROPYLENE COMPOSITION TOKUYAMA SODA CO LTD 1988-04-26 JP disclosed
JP-S6395245-A POLYPROPYLENE COMPOSITION TOKUYAMA SODA CO LTD 1988-04-26 JP disclosed
US-4711732-A Radiation-resistant grease JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1987-12-08 US disclosed
US-4711732-A Radiation-resistant grease JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1987-12-08 US disclosed
JP-S62109840-A POLYPROPYLENE COMPOSITION TOKUYAMA SODA CO LTD 1987-05-21 JP disclosed
US-4664829-A PHENOXYPHENOXYDIPHENYL AND MONOALKYL-OR DIALKYLDIPHENYL ETHER JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1987-05-12 US disclosed
JP-S59100197-A RADIATION-RESISTANT OIL JAPAN ATOM ENERGY RES INST 1984-06-09 JP disclosed
US-3957666-A HYDRAULIC FLUIDS, HEAT TRANSFER FLUIDS MONSANTO COMPANY (US) 1976-05-18 US disclosed
JP-S06395245-A 0001-01-01 JP disclosed
JP-S06395244-A 0001-01-01 JP disclosed