SCHEMBL112422

SCHEMBL112422

c1ccc(-c2ccccc2Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.63
NCOA3 Q9Y6Q9 1/20 0.63
MAPK1 P28482 2/20 0.52
TP53 P04637 1/20 0.52
RAB9A P51151 1/20 0.52
PTGS2 P35354 1/20 0.48
HRH1 P35367 1/20 0.48
HTR7 P34969 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CYP2A6 P11509 1/20 0.46
ADRB2 P07550 3/20 0.46
AR P10275 1/20 0.44
ADRB1 P08588 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL27922694 0.97 NCOA1 (0.61) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL28431579 0.97 NCOA1 (0.61) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL6321993 0.97 NCOA1 (0.61) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL10756496 0.97 NCOA1 (0.61) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL28436320 0.97 NCOA1 (0.61) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL2059488 0.95 NCOA1 (0.59) NCOA1NCOA3MAPK1TP53RAB9A
Ethylene Glycol SCHEMBL29029323 0.91 NCOA1 (0.55) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL2059490 0.90 NCOA1 (0.53) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL7791391 0.89 NCOA1 (0.69) NCOA1NCOA3MAPK1TP53RAB9A
SCHEMBL10755935 0.89 NCOA1 (0.69) NCOA1NCOA3MAPK1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES SYMRISE AG (DE) 2024-02-22 US claimed
WO-2024028266-A1 A PRESERVATIVE COMPOSITION BRAIN Biotech AG (DE) 2024-02-08 WO claimed
WO-2024028267-A1 A PRESERVATIVE COMPOSITION BRAIN Biotech AG (DE) 2024-02-08 WO claimed
WO-2024028265-A1 A PRESERVATION METHOD BRAIN Biotech AG (DE) 2024-02-08 WO claimed
EP-4316243-A1 A PRESERVATION METHOD BRAIN Biotech AG (DE) 2024-02-07 EP claimed
EP-4316461-A1 A PRESERVATIVE COMPOSITION BRAIN Biotech AG (DE) 2024-02-07 EP claimed
EP-4316459-A1 A PRESERVATIVE COMPOSITION BRAIN Biotech AG (DE) 2024-02-07 EP claimed
EP-4259287-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES Symrise AG (DE) 2023-10-18 EP claimed
CN-116583261-A Method for combating microorganisms using menthol derivatives 西姆莱斯股份公司 2023-08-11 CN claimed
CN-116120396-A Polypeptide and application thereof in preparation of preservative 华南协同创新研究院 2023-05-16 CN claimed
US-7582681-B2 Synergistic mixtures of 1,2-alkane diols SYMRISE GMBH & CO. KG (DE) 2009-09-01 US claimed
WO-2009088596-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-16 WO claimed
EP-1898952-A2 SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) Symrise GmbH & Co. KG (DE) 2008-03-19 EP claimed
US-20070054967-A1 SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) SYMRISE GMBH & CO. KG (DE) 2007-03-08 US claimed
WO-2006134160-A2 SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) SYMRISE GMBH & CO. KG (DE) 2006-12-21 WO claimed
EP-1478231-B1 SYNERGISTIC MIXTURES OF 1,2-ALKANE DIOLS SYMRISE GMBH & CO KG (DE) 2006-08-30 EP claimed
US-5439614-A Colloidal dispersion of aromatic ether and oxidation inhibiting amount of alkali metal salt of oxalic acid MONSANTO COMPANY (US) 1995-08-08 US claimed
US-4960884-A Insecticides, nematocides, pesticides and miticides FMC CORPORATION (US) 1990-10-02 US claimed
US-4070461-A ANTICHOLESTEROL MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-01-24 US claimed
US-4060609-A ANTICHOLESTEROL MERCH PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES MGLL, GCDH, GK NCOA1 1848/4885NCOA3 1858/4885MAPK1 3687/4885
US-20070054967-A1 SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) NR1H3, NR1H2, CBR3 NCOA1 248/4885NCOA3 294/4885MAPK1 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.