SCHEMBL7791404

SCHEMBL7791404

COc1ccc(/C=N/N=C/c2ccc(F)c(F)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
GRIN2D O15399 2/20 0.51
GRIN3B O60391 2/20 0.51
GRIN1 Q05586 2/20 0.51
GRIN2A Q12879 2/20 0.51
GRIN2B Q13224 2/20 0.51
GRIN2C Q14957 2/20 0.51
GRIN3A Q8TCU5 2/20 0.51
CHRM5 P08912 1/20 0.51
MIF P14174 1/20 0.49
NFE2L2 Q16236 4/20 0.47
CYP1A2 P05177 1/20 0.45
RRM1 P23921 1/20 0.43
RELA Q04206 2/20 0.42
S100B P04271 1/20 0.42
AHR P35869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791406 1.00 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7789082 0.87 AMY1A (0.52) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7789080 0.87 AMY1A (0.52) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7788332 0.87 GRIN2D (0.49) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792352 0.87 MAPT (0.54) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7788329 0.87 GRIN2D (0.49) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792357 0.87 MAPT (0.54) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7787981 0.86 GRIN2D (0.51) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7787983 0.86 GRIN2D (0.51) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7788423 0.85 GRIN2D (0.47) MAPTGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed