SCHEMBL7791405

SCHEMBL7791405

CCCCCCCc1cc(F)c(C=NN=Cc2ccc(Cl)cc2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 7/20 0.41
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
LMNA P02545 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
HIF1A Q16665 1/20 0.37
PTGS2 P35354 2/20 0.36
HTR2A P28223 1/20 0.36
MAOB P27338 1/20 0.35
RARB P10826 2/20 0.34
RARA P10276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791403 1.00 KCNH2 (0.41) KCNH2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783480 0.99 GRIN2D (0.40) KCNH2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783481 0.99 GRIN2D (0.40) KCNH2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792412 0.95 GRIN2D (0.44) KCNH2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792418 0.95 GRIN2D (0.44) KCNH2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783226 0.90 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7783225 0.90 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7792433 0.89 MAOB (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7792430 0.89 MAOB (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7783325 0.88 GRIN2D (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed