SCHEMBL7792433

SCHEMBL7792433

CCCc1cc(F)c(C=NN=Cc2ccc(Cl)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.39
GRIN2D O15399 3/20 0.37
GRIN3B O60391 3/20 0.37
GRIN1 Q05586 3/20 0.37
GRIN2A Q12879 3/20 0.37
GRIN2B Q13224 3/20 0.37
GRIN2C Q14957 3/20 0.37
GRIN3A Q8TCU5 3/20 0.37
POLB P06746 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
TRPA1 O75762 2/20 0.35
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
UBE2N P61088 2/20 0.34
CCR6 P51684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792430 1.00 MAOB (0.39) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792418 0.92 GRIN2D (0.44) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7792412 0.92 GRIN2D (0.44) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783480 0.91 GRIN2D (0.40) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7783481 0.91 GRIN2D (0.40) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7791931 0.90 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7791928 0.90 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7791405 0.89 KCNH2 (0.41) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7791403 0.89 KCNH2 (0.41) MAOBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7793625 0.88 MAOB (0.41) MAOBGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed