SCHEMBL7791480

SCHEMBL7791480

CC(C)(C)C1CCC(OC(=O)C(=O)Cl)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
HTT P42858 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP19A1 P11511 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 1/20 0.40
EPHX1 P07099 1/20 0.37
LIPA P38571 1/20 0.35
ENPP2 Q13822 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.33
EPHX2 P34913 1/20 0.33
HSD11B1 P28845 1/20 0.33
GPR35 Q9HC97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83128 0.84 MAPT (0.50) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL28970081 0.83
SCHEMBL7791477 0.83 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL22733771 0.79 MAPT (0.53) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL439526 0.79 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL22799034 0.79 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL28508307 0.79 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL27761051 0.79 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL25175298 0.78 MAPT (0.45) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2
SCHEMBL1552476 0.78 MAPT (0.51) MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
CN-1187487-A Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOCHEM NORTH AMERICA ELF (US) 1998-07-15 CN disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed