Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112776 | 0.93 | GRIN1 (0.58) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL20689725 | 0.89 | GRIN1 (0.66) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL13911257 | 0.89 | TAAR1 (0.57) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL20689708 | 0.89 | GRIN1 (0.66) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL20689710 | 0.89 | GRIN1 (0.66) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL23081526 | 0.89 | TAAR1 (0.57) | TAAR1AOC3GRIN1GRIN2AMEN1 | |
| SCHEMBL11922992 | 0.84 | KCNH2 (0.49) | TAAR1AOC3GRIN1GRIN2AALDH1A1 | |
| SCHEMBL8091786 | 0.82 | SIGMAR1 (0.60) | TAAR1MEN1KMT2ASIGMAR1 | |
| SCHEMBL11046082 | 0.82 | TAAR1 (0.68) | TAAR1AOC3MEN1KMT2ABCHE | |
| SCHEMBL9973173 | 0.81 | GRIN1 (0.72) | GRIN1GRIN2AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047097-A1 | Process for the preparation of arylethylamines by amination of arylolefins | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2001-11-29 | — | — | US | disclosed |
| EP-1157983-A1 | Process for the preparation of arylethylamines via the amination of arylolefins | Aventis Research & Technologies GmbH & Co KG (DE) | 2001-11-28 | — | — | EP | disclosed |