SCHEMBL7791809

SCHEMBL7791809

O=C1CCC([C@H]2CC[C@H](O)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.35
EPHX2 P34913 1/20 0.32
TRIM24 O15164 2/20 0.32
TRIM33 Q9UPN9 2/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.30
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791812 1.00 ESR2 (0.35) ESR2EPHX2TRIM24TRIM33TSHR
SCHEMBL19339444 1.00 ESR2 (0.35) ESR2EPHX2TRIM24TRIM33TSHR
SCHEMBL14864461 0.86 ESR2 (0.31) ESR2
SCHEMBL28670982 0.86 TRIM24 (0.41) ESR2TRIM24TRIM33ALDH1A1
SCHEMBL9234017 0.86 TRIM24 (0.41) ESR2TRIM24TRIM33ALDH1A1
SCHEMBL148906 0.83
SCHEMBL510704 0.83 TRIM24 (0.44) ESR2TRIM24TRIM33ALDH1A1
SCHEMBL11321611 0.79 ESR2 (0.35) ESR2TRIM24TRIM33ALDH1A1
SCHEMBL16769007 0.78 ALDH1A1 (0.47) ESR2TRIM24TRIM33ALDH1A1
SCHEMBL16769008 0.78 TRIM24 (0.42) ESR2TRIM24TRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001089470-A METHOD FOR PREPARING TRANS-4,4'-(4'-HYDROXYCYCLOHEXYL) CYCLOHEXANONE KETALS HONSHU CHEM IND CO LTD 2001-04-03 JP disclosed
JP-2001089413-A METHOD OF PRODUCING trans-4-(4'-OXOCYCLOHEXYL) CYCLOHEXANOLS HONSHU CHEM IND CO LTD 2001-04-03 JP disclosed