SCHEMBL7791817

SCHEMBL7791817

Cc1sc([Si](C)(C)C)cc1Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1D1 P20393 1/20 0.33
NR1H3 Q13133 1/20 0.33
HCAR3 P49019 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382727 0.78 GSK3B (0.33)
SCHEMBL771887 0.78
SCHEMBL16623404 0.74
SCHEMBL16605146 0.74
SCHEMBL19718303 0.70 NPC1 (0.33)
SCHEMBL12228811 0.70
SCHEMBL566671 0.69
SCHEMBL4627777 0.69 HCAR3 (0.32) HCAR3HCAR2
SCHEMBL2812953 0.69
SCHEMBL19704631 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300142-A Dithienylethylene fluorescent molecular switch regulated and controlled by visible light, and preparation and application thereof 华中科技大学 2021-02-02 CN claimed
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
WO-2024212024-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
WO-2024212907-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
CN-112409324-B Visible light controlled perfluoro-substituted dithienyl vinyl compound, preparation and application thereof 华中科技大学 2022-02-11 CN disclosed
CN-112300142-B Dithienylethylene fluorescent molecular switch regulated and controlled by visible light, and preparation and application thereof 华中科技大学 2021-11-30 CN disclosed
WO-2021056686-A1 PHOTOCHROMIC MATERIAL, PREPARATION METHOD THEREFOR AND CONTACT LENSES THEREOF 海昌隐形眼镜有限公司 2021-04-01 WO disclosed
CN-112409324-A Visible light controlled perfluoro-substituted dithienyl vinyl compound, preparation and application thereof 华中科技大学 2021-02-26 CN disclosed
CN-112300142-A Dithienylethylene fluorescent molecular switch regulated and controlled by visible light, and preparation and application thereof 华中科技大学 2021-02-02 CN disclosed
CN-110698676-A Photochromic material, preparation method and contact lens 海昌隐形眼镜有限公司 2020-01-17 CN disclosed
EP-0698605-B1 Thiophene derivatives and polymers thereof JAPAN RES DEV CORP (JP) 2001-11-21 EP disclosed
US-5734065-A Thiophene derivative and the polymer thereof and methods for production thereof RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1998-03-31 US disclosed
EP-0698605-A1 Thiophene derivatives and polymers thereof RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1996-02-28 EP disclosed