Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 5/20 | 0.47 |
| ▸ | TACR1 | P25103 | 5/20 | 0.47 |
| ▸ | TACR3 | P29371 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200433 | 0.85 | CCR5 (0.51) | CCR5TACR2TACR1TACR3CYP3A4 | |
| Hydrochloric Acid SCHEMBL6490695 | 0.84 | CCR5 (0.50) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5203138 | 0.82 | TACR2 (0.51) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5199990 | 0.81 | CCR5 (0.54) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5200438 | 0.80 | SLC6A2 (0.51) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5200182 | 0.80 | TACR2 (0.52) | CCR5TACR2TACR1TACR3 | |
| SCHEMBL5203186 | 0.79 | CCR5 (0.54) | CCR5TACR2TACR1TACR3 | |
| SCHEMBL5199904 | 0.78 | CCR5 (0.53) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5201070 | 0.78 | CCR5 (0.49) | CCR5TACR2TACR1TACR3CYP3A4 | |
| SCHEMBL5199623 | 0.78 | CCR5 (0.53) | CCR5TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150970-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047572-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2000-08-17 | — | — | WO | disclosed |