Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL30584157 | 1.00 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| Zinc Ion SCHEMBL28338907 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL30001720 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL4103991 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL4099227 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| Potassium Ion SCHEMBL4088712 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL30001741 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL4102818 | 0.96 | GPR35 (0.56) | GPR35TSHRALDH1A1CTSDTDP1 | |
| Lithium Ion SCHEMBL7791976 | 0.87 | TSHR (0.66) | GPR35TSHRALDH1A1CTSDTDP1 | |
| SCHEMBL7417028 | 0.85 | GPR35 (0.60) | GPR35TSHRALDH1A1CTSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116826208-A | Lithium supplementing positive electrode material, preparation method and application of lithium nitrobenzoate, lithium ion battery and electric equipment | 蜂巢能源科技(无锡)有限公司 | 2023-09-29 | — | — | CN | claimed |
| JP-8105899-A | — | — | None | — | — | JP | disclosed |
| CN-116826208-A | Lithium supplementing positive electrode material, preparation method and application of lithium nitrobenzoate, lithium ion battery and electric equipment | 蜂巢能源科技(无锡)有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-0703453-B1 | Method for the determination of creatinine and urinary protein | BAYER AG (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0703453-A1 | Dry reagent for creatinine assay | Bayer Corporation (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5464777-A | Dry reagent for creatinine assay | MILES INC. (US) | 1995-11-07 | — | — | US | disclosed |