Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796400 | 0.97 | MAPT (0.42) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7791994 | 0.93 | TTR (0.40) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7794705 | 0.92 | NPY1R (0.41) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7794745 | 0.91 | KCNA3 (0.46) | ITGB3ITGA2BKCNA3SLC6A2SLC6A4 | |
| SCHEMBL7792388 | 0.90 | ACP1 (0.41) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7786391 | 0.90 | HTR2A (0.42) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7786238 | 0.90 | HTR2A (0.42) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7792363 | 0.90 | HTR2A (0.47) | HTR2AHTR2CHTR2BKCNA3NPY1R | |
| SCHEMBL7792449 | 0.89 | KCNA3 (0.41) | HTR2AHTR2CHTR2BITGB3ITGA2B | |
| SCHEMBL7794712 | 0.88 | KCNA3 (0.47) | ITGB3ITGA2BKCNA3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |