Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794745 | 0.97 | KCNA3 (0.46) | KCNA3ITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL7786473 | 0.94 | ITGB3 (0.50) | KCNA3ITGB3ITGA2BSLC6A4TERT | |
| SCHEMBL7792589 | 0.91 | KCNA3 (0.44) | KCNA3ITGB3ITGA2BNPY1R | |
| SCHEMBL7796400 | 0.89 | MAPT (0.42) | KCNA3ITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL7792411 | 0.88 | HTR2A (0.41) | KCNA3ITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL7791994 | 0.87 | TTR (0.40) | KCNA3ITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL7792388 | 0.86 | ACP1 (0.41) | KCNA3ITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL7796437 | 0.86 | KCNA3 (0.48) | KCNA3ITGB3ITGA2BNPY1RTERT | |
| SCHEMBL7792449 | 0.84 | KCNA3 (0.41) | KCNA3ITGB3ITGA2BSLC6A4NPY1R | |
| SCHEMBL7794705 | 0.84 | NPY1R (0.41) | KCNA3NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0906268-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045397-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-04 | — | — | WO | disclosed |