Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794786 | 0.99 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TSHRKDM4EMEN1 | |
| SCHEMBL7796117 | 0.95 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TSHRKDM4EMEN1 | |
| SCHEMBL7792004 | 0.94 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4EMEN1PKM | |
| SCHEMBL7794777 | 0.94 | HRH3 (0.46) | ALDH1A1L3MBTL1KDM4EMEN1PKM | |
| SCHEMBL7795879 | 0.94 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KDM4EADORA2AADORA1 | |
| SCHEMBL7792444 | 0.94 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KDM4EADORA2AADORA1 | |
| SCHEMBL7792361 | 0.93 | CYP2D6 (0.44) | ALDH1A1L3MBTL1KDM4EMEN1PKM | |
| SCHEMBL7792690 | 0.93 | HRH3 (0.45) | ALDH1A1L3MBTL1KDM4EMEN1PKM | |
| SCHEMBL7795701 | 0.92 | HRH3 (0.49) | ALDH1A1KDM4EMEN1PKMKMT2A | |
| SCHEMBL7796421 | 0.91 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4EADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |