⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008849 | 0.78 | — | — | |
| SCHEMBL6173510 | 0.74 | — | — | |
| SCHEMBL9233465 | 0.74 | — | — | |
| SCHEMBL1362233 | 0.73 | — | — | |
| SCHEMBL7309994 | 0.72 | FAAH (0.46) | — | |
| SCHEMBL6637834 | 0.71 | — | — | |
| SCHEMBL217829 | 0.71 | — | — | |
| SCHEMBL241831 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL5710352 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL54034 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414084-A | Reaction 2-aminopyrimidine or amino-1,3,5-triazine derivative; purity; by-product inhibition | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | claimed |
| US-4981864-A | ANTICOAGULANTS | BOEHRINGER MANNEHIM GMBH (DE) | 1991-01-01 | — | — | US | claimed |
| EP-3444238-B1 | PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS | SATO PHARMA (JP) | 2021-12-08 | — | — | EP | disclosed |
| CN-107428700-B | 9-membered fused ring derivative | 盐野义制药株式会社 | 2021-08-03 | — | — | CN | disclosed |
| EP-3444238-A2 | PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS | Sato Pharmaceutical Co., Ltd. (JP) | 2019-02-20 | — | — | EP | disclosed |
| EP-2878594-B1 | DIFLUOROMETHYLENE COMPOUND | SATO PHARMA (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9701642-B2 | Method for producing optically active 5-hydroxy-3-ketoester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-9650380-B2 | Difluoromethylene compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2017-05-16 | — | — | US | disclosed |
| US-20170044158-A1 | DIFLUOROMETHYLENE COMPOUND | SATO PHARMACEUTICAL CO., LTD. (JP) | 2017-02-16 | — | — | US | disclosed |
| US-9512119-B2 | Difluoromethylene compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20160185734-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 5-HYDROXY-3-KETOESTER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-06-30 | — | — | US | disclosed |
| EP-0207483-A2 | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0186010-A1 | Pyrrolo benzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1986-07-02 | — | — | EP | disclosed |
| EP-0185345-A1 | Imidazo derivatives, their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |
| EP-0185346-A2 | Imidazo derivatives, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |
| US-4582837-A | Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity | DR. KARL THOMAE GMBH (DE) | 1986-04-15 | — | — | US | disclosed |
| EP-0130461-A2 | Imidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-01-09 | — | — | EP | disclosed |
| EP-0098448-A2 | Imidazole derivatives, their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1984-01-18 | — | — | EP | disclosed |
| US-4160643-A | FOR POLYMERS OF ACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |
| US-4111929-A | POLYACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |