Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792209 | 0.97 | HTR2A (0.41) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7792711 | 0.95 | HTR2A (0.38) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7792631 | 0.92 | HTR2A (0.39) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7794788 | 0.91 | TTR (0.42) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL7786129 | 0.91 | KCNA3 (0.36) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7795846 | 0.91 | HTR2A (0.36) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7794865 | 0.90 | HTR2A (0.35) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7795933 | 0.90 | SLC6A2 (0.41) | HTR2AHTR2CHTR2BKCNA3SLC6A2 | |
| SCHEMBL7786028 | 0.89 | KMT2A (0.38) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7792340 | 0.88 | KCNA3 (0.37) | HTR2AHTR2CHTR2BKCNA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |