Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396731 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL7651529 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18740274 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18740272 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18758545 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL2200157 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL4739425 | 0.78 | KMT2A (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTNPC1 | |
| Etocrylene SCHEMBL1768864 | 0.77 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| Etocrylene SCHEMBL39390 | 0.77 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL8076180 | 0.77 | MAPT (0.56) | SMN1; SMN2ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823435-B1 | Phosphites, process for producing the same and their use | SUMITOMO CHEMICAL CO (JP) | 2001-11-21 | — | — | EP | disclosed |