SCHEMBL7792909

SCHEMBL7792909

CC(=O)NSCC1CN(c2ccc(N3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 7/20 0.61
MAOB P27338 10/20 0.57
MAOA P21397 4/20 0.57
PTGS1 P23219 2/20 0.57
SDHA P31040 2/20 0.57
LMNA P02545 1/20 0.57
CALML3 P27482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792905 1.00 F10 (0.61) F10MAOBMAOAPTGS1SDHA
SCHEMBL6156987 0.91 F10 (0.61) F10MAOBMAOAPTGS1SDHA
SCHEMBL27463745 0.91 F10 (0.61) F10MAOBMAOAPTGS1SDHA
SCHEMBL17205733 0.87 MAOB (0.75) F10MAOBMAOAPTGS1SDHA
SCHEMBL17205732 0.87 MAOB (0.75) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL1176950 0.86 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
SCHEMBL6163637 0.86 MAOB (0.75) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL186562 0.86 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL29421647 0.86 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
SCHEMBL6160302 0.86 MAOB (0.75) F10MAOBMAOAPTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010041728-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality HESTER JACKSON B (US) 2001-11-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041728-A1 Oxazolidinone antibacterial agents having a thiocarbonyl functionality OXA1L, MRPL21, TOP1 F10 3383/4885MAOB 2998/4885MAOA 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.