Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.76 |
| ▸ | MAOA | P21397 | 5/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.76 |
| ▸ | SDHA | P31040 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CALML3 | P27482 | 1/20 | 0.76 |
| ▸ | F10 | P00742 | 6/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eperezolid SCHEMBL1176950 | 1.00 | MAOB (0.76) | MAOBMAOAPTGS1SDHALMNA | |
| Eperezolid SCHEMBL186562 | 1.00 | MAOB (0.76) | MAOBMAOAPTGS1SDHALMNA | |
| Eperezolid SCHEMBL5325217 | 0.99 | MAOB (0.75) | MAOBMAOAPTGS1SDHALMNA | |
| Eperezolid SCHEMBL5328753 | 0.96 | F10 (0.71) | MAOBMAOAPTGS1SDHALMNA | |
| Eperezolid SCHEMBL7497950 | 0.96 | MAOB (0.85) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6160239 | 0.94 | F10 (0.72) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6160243 | 0.94 | F10 (0.72) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL4163039 | 0.93 | MAOA (0.67) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL10151505 | 0.93 | MAOB (0.76) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL12674054 | 0.92 | MAOB (0.73) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250191691-A1 | METHODS FOR THE TRANSLATED ALIGNMENT OF TRANSCRIPTOMIC DATA AT SINGLE-CELL RESOLUTION | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2025-06-12 | — | — | US | disclosed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| CN-117222433-A | Medicaments conjugated to hexose phosphate and methods of making and using the same | 密西西比州立大学 | 2023-12-12 | — | — | CN | disclosed |
| US-20230372492-A1 | DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME | MISSISSIPPI STATE UNIVERSITY (US) | 2023-11-23 | — | — | US | disclosed |
| EP-4221755-A1 | DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME | Mississippi State University (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-116568336-A | Drug conjugates and uses thereof | 休伯特兰斯医疗有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-20220112203-A1 | SMALL MOLECULES ACTIVE AGAINST GRAM-NEGATIVE BACTERIA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-14 | — | — | US | disclosed |
| WO-2022072425-A1 | DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME | PARK JOO YOUN (US) | 2022-04-07 | — | — | WO | disclosed |
| CN-114206362-A | Methods of treating inflammatory conditions and related infections | 赛瓦图斯有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372492-A1 | DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME | GFPT1, PHPT1, SLC2A1 | MAOB 3136/4885MAOA 2364/4885PTGS1 3999/4885 |
| US-20220112203-A1 | SMALL MOLECULES ACTIVE AGAINST GRAM-NEGATIVE BACTERIA | PGLS, MRPL21, CLPP | MAOB 503/4885MAOA 701/4885PTGS1 2694/4885 |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | PGLS, MRPL21, CLPP | MAOB 503/4885MAOA 701/4885PTGS1 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.