Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908580 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BPRCPSIGMAR1 | |
| SCHEMBL7035041 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BPRCPSIGMAR1 | |
| SCHEMBL5959164 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BPRCPSIGMAR1 | |
| SCHEMBL28326008 | 1.00 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BPRCPSIGMAR1 | |
| SCHEMBL23673709 | 0.91 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11124856 | 0.91 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL5154379 | 0.91 | GRIN2D (0.33) | GRIN1GRIN2AGRIN2BPRCPSIGMAR1 | |
| SCHEMBL11121877 | 0.91 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7828829 | 0.88 | — | — | |
| SCHEMBL5154283 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-B1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2001-12-19 | — | — | EP | disclosed |
| US-6174879-B1 | BLOCKING SODIUM AND POTASSIUM ION CHANNELS IN VIVO AND IN VITRO; ANTIARRHYTHMIA AGENTS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-01-16 | — | — | US | disclosed |
| EP-0632806-B1 | AMINOCYCLOHEXYLAMIDES FOR ANTIARRHYTHMIC AND ANAESTHETIC USES | UNIV BRITISH COLUMBIA (CA) | 1997-07-02 | — | — | EP | disclosed |
| EP-0632806-A1 | AMINOCYCLOHEXYLAMIDES FOR ANTIARRHYTHMIC AND ANAESTHETIC USES. | UNIV BRITISH COLUMBIA (CA) | 1995-01-11 | — | — | EP | disclosed |
| WO-1993019056-A1 | AMINOCYCLOHEXYLAMIDES FOR ANTIARRHYTHMIC AND ANAESTHETIC USES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1993-09-30 | — | — | WO | disclosed |
| US-4886812-A | REGULATING DOPAMINE CONCENTRATION; PARKINSON DISEASE, HYPOTENSIVE AGENT, SCHIZOPHRENIA | DR. KARL THOMAE GMBH (DE) | 1989-12-12 | — | — | US | disclosed |