Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857852 | 0.83 | FDPS (0.41) | FDPSHDAC1HDAC6 | |
| SCHEMBL27554271 | 0.82 | FDPS (0.47) | FDPSHDAC1HDAC6 | |
| SCHEMBL595230 | 0.81 | FDPS (0.46) | FDPSHDAC1HDAC6 | |
| SCHEMBL5989432 | 0.77 | FDPS (0.51) | FDPSHDAC1HDAC6 | |
| SCHEMBL9104259 | 0.77 | FDPS (0.39) | FDPS | |
| SCHEMBL29139986 | 0.72 | FDPS (0.47) | FDPSHDAC1HDAC6 | |
| SCHEMBL28272 | 0.69 | FDPS (0.44) | FDPSHDAC1HDAC6 | |
| SCHEMBL2676961 | 0.69 | FDPS (0.44) | FDPSHDAC1HDAC6 | |
| SCHEMBL28139965 | 0.67 | FGFR1 (0.43) | FDPS | |
| SCHEMBL9103883 | 0.66 | FDPS (0.41) | FDPSHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646243-B1 | DETECTION OF ALZHEIMER'S DISEASE AND AMYOTROPHIC LATERAL SCLEROSIS USING A PHOTOAFFINITY LABELING METHOD | UNIV KENTUCKY RES FOUND (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0728216-A4 | DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD | UNIV KENTUCKY RES FOUND (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0728216-A1 | DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5445937-A | Detection of Alzheimer's disease and other diseases using an improved photoaffinity labeling method | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1995-08-29 | — | — | US | disclosed |
| WO-1995011314-A1 | DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1995-04-27 | — | — | WO | disclosed |
| EP-0646243-A1 | DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING A PHOTOAFFINITY LABELING METHOD | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5272055-A | Detection of Alzheimer's disease and other diseases using a photoaffinity labeling method | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1993-12-21 | — | — | US | disclosed |
| WO-1993012755-A2 | DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING A PHOTOAFFINITY LABELING METHOD | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1993-07-08 | — | — | WO | disclosed |