Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639267 | 0.86 | CTRC (0.54) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL4281038 | 0.83 | PPARG (0.40) | CTRCPPARGPPARACA12CA9 | |
| SCHEMBL568454 | 0.81 | CTRC (0.50) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL11521450 | 0.81 | KMT2A (0.53) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL568643 | 0.81 | CTRC (0.50) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL14565994 | 0.81 | CTRC (0.50) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL4654231 | 0.80 | PPARG (0.59) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL19717843 | 0.80 | KDM4E (0.56) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL9322236 | 0.80 | CTRC (0.49) | CTRCPPARGPTGESALOX5PPARA | |
| SCHEMBL547407 | 0.80 | KDM4E (0.56) | CTRCPPARGPTGESALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |