⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154206 | 0.86 | KDM5A (0.33) | — | |
| SCHEMBL2962393 | 0.79 | CA12 (0.50) | — | |
| SCHEMBL17401242 | 0.79 | CA12 (0.32) | — | |
| SCHEMBL789797 | 0.78 | KMT2A (0.45) | — | |
| SCHEMBL22294054 | 0.77 | — | — | |
| SCHEMBL425201 | 0.77 | — | — | |
| SCHEMBL7489795 | 0.77 | S1PR2 (0.46) | — | |
| SCHEMBL6199544 | 0.77 | S1PR2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL3205113 | 0.76 | KMT2A (0.43) | — | |
| SCHEMBL25828235 | 0.76 | PIK3CD (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968589-B2 | Method of treating disease by auricular anesthesia of cranial nerves | CREWS THOMAS M (US) | 2018-05-15 | — | — | US | disclosed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | disclosed |