Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793568 | 1.00 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792165 | 0.89 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792161 | 0.89 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7783599 | 0.87 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7783596 | 0.87 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792488 | 0.85 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7792491 | 0.85 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7788577 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7788573 | 0.83 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7788428 | 0.82 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |