Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043402 | 1.00 | CYP2D6 (0.47) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL7041122 | 0.94 | BCHE (0.46) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL7041125 | 0.94 | BCHE (0.46) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL12942195 | 0.92 | BCHE (0.45) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL16404499 | 0.87 | GJB2 (0.42) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL15837031 | 0.87 | GJB2 (0.42) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL16508371 | 0.87 | BCHE (0.41) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL18744562 | 0.86 | GJB2 (0.43) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL3344752 | 0.85 | BCHE (0.43) | CYP2D6THRBHSD17B10CA2BCHE | |
| SCHEMBL3344756 | 0.85 | BCHE (0.43) | CYP2D6THRBHSD17B10CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | TOWNSEND LEROY B (US) | 2001-08-02 | — | — | US | disclosed |
| US-5874413-A | CYTOMEGALO VIRUS | UNIVERSITY OF MICHIGAN (US) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | ZC3HAV1, ZC3HAV1L, IFNAR1 | CYP2D6 515/4885THRB 3675/4885HSD17B10 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.