Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.47 |
| ▸ | RARG | P13631 | 11/20 | 0.47 |
| ▸ | RARA | P10276 | 11/20 | 0.47 |
| ▸ | RXRA | P19793 | 7/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945444 | 0.92 | RARB (0.53) | RARBRARGRARARXRARXRB | |
| SCHEMBL7792840 | 0.90 | RARG (0.59) | RARBRARGRARARXRARXRB | |
| SCHEMBL7790156 | 0.88 | RARG (0.50) | RARBRARGRARARXRARXRB | |
| SCHEMBL7792837 | 0.87 | RARB (0.60) | RARBRARGRARARXRARXRB | |
| SCHEMBL7794287 | 0.87 | RARB (0.60) | RARBRARGRARARXRARXRB | |
| SCHEMBL7784309 | 0.87 | RARB (0.60) | RARBRARGRARARXRARXRB | |
| SCHEMBL7793745 | 0.86 | RARB (0.46) | RARBRARGRARARXRAEGFR | |
| SCHEMBL2917040 | 0.86 | RARB (0.65) | RARBRARGRARARXRARXRB | |
| SCHEMBL2944374 | 0.83 | EGFR (0.52) | RARBRARGRARARXRAEGFR | |
| SCHEMBL2937025 | 0.83 | RARG (0.58) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |